Efficacy of bright light treatment, fluoxetine, and the combination in patients with nonseasonal major depressive disorder: A randomized clinical trial
JAMA Psychiatry, 11/25/2015 Clinical Article
Lam RW, et al.
A new study indicates bright light Rx alone or in combination with Prozac were helpful in major depressive disorder (MDD), whereas Prozac alone was not.
According to Dr. Harold Levinson, this interesting study suggests adding light Rx to the pharmacological treatment of depressed patients when the desired improvements are inadequate. Moreover, these results indicate that light may be helpful for all depressed individuals and/or that the differentiation of seasonal vs. nonseasonal depression is subject to significant error.
Levinson’s clinical experience with light Rx and/or large doses of vitamin D in a few seemingly “nonseasonal” depressives refractory to medications tends to corroborate the study’s results. It is also important to recognize that there often coexists overlapping mechanisms contributing to depressive and anxiety symptoms, eg., cerebellar dysfunctioning and high inflammation triggers. Thus combined therapies provide the best results.
About Dr. Harold Levinson
Formerly Clinical Associate Professor of Psychiatry at New York University Medical Center, Dr. Harold Levinson is currently Director of the Levinson Medical Center for Learning Disabilities in Long Island, New York. He is a well-known neuropsychiatrist, clinical researcher and author. For more information, call 1(800)334-7323 or
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